Magnesium sulfate in ampoules. Magnesium Sulfate: instructions for use. Safe Cleaning Instructions.


Magnesium sulfate powder: instructions for use

Compound

Magnesium sulfate - 10 g or 20 g.

Description

colorless prismatic crystals that weather in the air.

pharmachologic effect

When taken orally, it has a choleretic effect (a reflex effect on the receptors of the duodenal mucosa) and a laxative effect (due to poor absorption of the drug in the intestine, a high osmotic pressure is created in it, water accumulates in the intestine, the intestinal contents liquefy, peristalsis increases). It is an antidote for poisoning with salts of heavy metals.

This is because there is not enough magnesium to relax the heart and make it ready for the next contraction. The normal function of healthy tissue depends on a balance between the ability to contract and relax. Keep in mind that football, another essential mineral, is not absorbed into the body without magnesium. Calcium therefore, should never be taken alone, otherwise it will eliminate magnesium from various parts of the body in order to be assimilated. This is what happens to those who eat dairy products and those who drink milk. milk is about eight parts calcium with magnesium, this will lead to magnesium deficiency. "excess calcium in your body will form deposits such as gallstones, kidney stones, calcium deposits in the joints causing" arthritis.

The onset of the effect is after 0.5-3 hours, the duration is 4-6 hours.

Pharmacokinetics

When taken orally, it is poorly absorbed (no more than 20%) in the jejunum and ileum, reabsorbed from bile, pancreatic and intestinal juice; with malabsorption syndrome and eating, rich in fat, the absorption of Mg 2+ is reduced. Communication with intracellular proteins and macroergic phosphates - 30%. TS max - 4 hours. Mg 2+ is deposited in bones, skeletal muscles, kidneys, liver and myocardium; v small quantities in tissue fluid and erythrocytes. Penetrates through the blood-brain and placental barrier, creates concentrations in breast milk that are 2 times higher than those in plasma. Excretion is carried out by the kidneys (the rate of excretion by the kidneys is proportional to plasma concentration and glomerular filtration rate) and with feces.

As magnesium levels recover, they tend to contain allergic manifestations. When magnesium was inhaled through an aerosol, the threshold of histamine-dependent bronchial reactivity decreased; The introduction of magnesium prevents induced bronchial constriction. Overactivation of the pathology of this enzyme causes problems in absorptive and bone calcium fixation, as well as bone marrow calcification. This is no longer the secretly defining role of magnesium in calcium fixation in the bones for those who have read the medical literature received over the past five years.

Indications for use

Applied occasionally as a laxative for constipation, to prepare for studies of the large intestine and for poisoning with soluble barium salts.

Contraindications

Hypersensitivity; appendicitis; rectal bleeding (including suspected); intestinal obstruction; acute inflammatory diseases of the gastrointestinal tract; colitis; cholelithiasis, obstruction of the biliary tract; dehydration, hypermagnesemia; conditions associated with calcium deficiency and depression of the respiratory center; acute febrile conditions; arterial hypotension; severe renal failure; pregnancy.

There are cases when prostate anomalies sometimes recede to complete normality. Once improvement is achieved, magnesium chloride is administered at lower doses: for prophylaxis. In the same patients, if magnesium supplementation is supplemented with a specific drug, cholesterol reduction averages 20%. Diabetes creates an inevitable progressive loss of magnesium. The greater the depletion of magnesium tissue, the more important the so-called complications of diabetes. Liebscher writes: "All diabetic patients should receive magnesium supplements because this can better control insulin and symptoms at any time."

Pregnancy and lactation

The drug is contraindicated in pregnancy. During lactation, take under medical supervision if the benefit to the mother outweighs the risk to the baby.

Dosage and administration

Inside is prescribed as a laxative (at night or on an empty stomach - half an hour before meals) for adults, dissolve 10-30 g of powder in 100 ml of warm boiled water, children over 12 years old - 10 g in 100 ml of warm boiled water, children 6-12 years old are prescribed from 5 g to 10 g dissolved in warm boiled water at the rate of 10 g of magnesium sulfate per 100 ml of water. For chronic constipation - enemas (20-30 g of powder dissolved in 100 ml of warm boiled water).

The symptoms that diabetics improve with magnesium supplementation are, according to the medical literature, hypertension, neurological complications, cardiac complications, eye complications, muscle complications, depression, etc. in some cases, even insulin control and the amount of insulin administered can be improved or cured with magnesium administration, and the fact is that low magnesium levels in turn are insulin resistance. After three months, my agility level increased even more.

Sciatica was won: an explanation? The nervous system became calm, shiny, the blood was decalcified, and the fluid The most common sharp lancets in the liver disappeared. Hundreds of people have been healed here at St. Catherine's College in Florianopolis after years of suffering from spinal pain, arthrosis, etc. and many of them are talking to others who have despaired. Cox demonstrates the role of magnesium in chronic asthenia syndrome: it has been shown that erythrocyte magnesium levels in this condition are low, and that magnesium administration leads to a state of well-being in these patients.

How cholagogue appoint 1 tablespoon of the solution (20 g of powder dissolved in 100 ml of warm boiled water) 3 times a day; duodenal sounding is also performed with the introduction of a warm solution of magnesium sulfate through the probe (50 ml of a 25% solution or 100 ml of a 10% solution).

In case of poisoning with salts of heavy metals, the stomach is washed with a 1% solution of magnesium sulfate or given orally (20-25 g in 200 ml of water). The maximum dose for adults is up to 40 g / day.

Schorr of Santa Caterina College Professor of Physics, Chemistry and Biology. Once mixed, store well in glass containers rather than plastic containers. The dose is equivalent to a cup of coffee. People now have no hope of recovery from the so-called "parrot's beak" evil, from the evil to the sciatic nerve, spinal evil and calcification, there is now an effective treatment, painless, simple and no. expensive. It was a "parrot's beak", incurable according to the doctor. With this rheumatic pain, he healed me with Ketacil.

Five years later, despite treatment, my right leg made me worse. Meanwhile, the "parrots" progressed painfully. The use of microwaves and tension of the spinal cord did not stop the pain. Father Suarez told me that nursing with Magnesium Chloride was easy and showed me a booklet opened by Father Puig, a Spanish Jesuit. With the application of this salt, he became agile like a girl. Back in Florianopolis, took a dose every morning. Three days later, taken at a dose in the morning and one evening. My pulse, which had previously been less than 40 beats, returned to normal.

Side effect

Nausea, vomiting, diarrhea, exacerbation inflammatory diseases Gastrointestinal tract, electrolyte imbalance (fatigue, asthenia, confusion, arrhythmia, convulsions), flatulence, spastic abdominal pain, thirst, signs of hypermagnesemia in the presence of renal failure (dizziness).

My nervous system is recovering and much more polished. blood, decalcified, is a liquid. frequent sharp pains in the liver disappeared. It may happen that the body, of various nature diseases or deficiencies in need of it. In these cases, magnesium may be taken as well with some food products, and also diluted in water in the form of magnesium chloride. Magnesium and A are an important natural element for both organisms. animal and vegetable ones. in the plant world, magnesium and the core around which chlorophyll is built, the green pigment is necessary for the life of the vast majority of plants.

Early signs and symptoms of hypermagnesemia: bradycardia, diplopia, sudden "rush" of blood to the skin of the face, headache, decreased blood pressure, nausea, shortness of breath, blurred speech, vomiting, weakness.

Signs of hypermagnesemia (in order of increasing concentrations of Mg 2+ in the blood serum): a decrease in deep tendon reflexes (2-3.5 mmol / l), lengthening of the P-Q interval and expansion of the QRS complex on the ECG (2.5-5 mmol / l ), loss of deep tendon reflexes (4-5 mmol/l), depression of the respiratory center (5-6.5 mmol/l), impaired conduction of the heart (7.5 mmol/l), cardiac arrest (12.5 mmol/l ). In addition, hyperhidrosis, anxiety, deep sedation, polyuria, uterine atony.

Method of application and dosing regimen

Thanks to chlorophyll, those that allow the plant to live and grow can occur. In fact, it is necessary to activate hundreds of chemical reactions. Our body contains about 25 grams of magnesium, mainly located in the bones in the muscles, brain and other organs such as the liver, kidneys and testicles. Its deficiency manifests itself in a wide variety of symptoms, from agitation to anxiety to muscular hyperexcitability, from headache to dizziness, from insomnia to asthma, from changes in heart rate to excessive fatigue from menstrual irregularities.

Overdose

Symptoms: severe diarrhea, vomiting.

Treatment: symptomatic.

Interaction with other drugs

Reduces the effect of oral anticoagulants (including coumarin derivatives or indandione derivatives), cardiac glycosides, phenothiazines (especially chlorpromazine).

Reduces the absorption of ciprofloxacin, etidronic acid, antibiotics of the tetracycline group (forms unabsorbed complexes with oral tetracyclines), weakens the effect of streptomycin and tobramycin (laxatives Mg 2+ -containing medicines should be taken 1-2 hours after the use of the above drugs).

In the last century, medical research has been concerned with the therapeutic use of magnesium and, in connection with this, interesting experiments have been carried out. For example, it has recently been found that magnesium intake in the first two weeks after a heart attack can reduce mortality by 55%. Women with osteoporosis experienced 87% bone loss after two years of magnesium supplementation. He tried various mineral solutions and found that the magnesium chloride solution was not only harmless to tissues, but also had big influence on the activity of leukocytes and phagocytosis, so it is ideal for the treatment of external wounds.

Pharmaceutically incompatible (precipitate forms) with drugs Ca 2+, ethanol (in high concentrations), carbonates, bicarbonates and phosphates of alkali metals, salts of arsenic acid, barium, strontium, clindamycin phosphate, sodium hydrocortisone succinate, polymyxin B sulfate, procaine hydrochloride, salicylates and tartrates.

Until then, he received the message, very good therapeutic effects of this "therapy" people who have magnesium chloride for its tonic properties and who suffer from various diseases. Colitis, cholangitis and cholecystitis in the gastrointestinal tract, Parkinson's disease, senile tremors and muscle spasms in nervous system, acne, eczema, psoriasis, warts, itching of various origins and frostbite in the skin. In experimental studies, magnesium chloride solution can also delay the progression of cancer in laboratory animals.

The first well-documented report of all his studies on magnesium chloride. To his surprise, the next day, when lab results confirmed the diagnosis of diphtheria, the child was completely healed before using the serum. All patients were treated within a very short time, without complications. As magnesium chloride has no direct effect on bacteria, Neveu considered that its action was non-specific, immuno-enhancing, so it could be useful in a similar way against viral diseases as well.

Self-medication can be harmful to your health.
It is necessary to consult a doctor, and also read the instructions before use.

MAGNESIUM SULFATE, powder for oral solution 10g and 20g

International non-proprietary name

So she began treatment for some cases of polio, and had the same excellent results. He was very agitated and tried to publicize the therapy, but he ran into a wall of hostility and obstruction from "official medicine". But the indications for magnesium chloride therapy do not end there. The previous list of disorders is by no means exhaustive, it is possible that other diseases can be cured by this therapy, but since this is a relatively "young" treatment, we are pioneers and we need the help of all doctors who want to establish definitely all the true possibilities of this wonderful therapy.

Magnesium sulfate.

magnesium sulfate.

Pharmacotherapeutic group

Laxative.

Compound: magnesium sulfate 10 g or 20 g.

ATX code: A06AD04.

pharmachologic effect

When taken orally, it has a choleretic effect (a reflex effect on the receptors of the duodenal mucosa) and a laxative effect (due to poor absorption of the drug in the intestine, a high osmotic pressure is created in it, water accumulates in the intestine, the intestinal contents liquefy, peristalsis increases). It is an antidote for poisoning with salts of heavy metals.

From a practical point of view, please remember that only magnesium chloride is "cytophylactic" activity, and no magnesium salt can be molecular, not just an ionic matter. The solution used is a 2.5% solution of magnesium chloride hexahydrate.

Since magnesium chloride has a weak laxative effect, diarrhea sometimes appears in the first days of therapy, especially if high doses have been taken, but this is not a reason to stop therapy. The taste of the solution is not very good, so some juice can be added to the solution or it can be used instead of water to make the solution itself. Masks for grapefruit juice, bitter taste is very good. As a preventive measure and as a magnesium supplement, the daily dose can be taken indefinitely.

The onset of the effect is after 0.5-3 hours, the duration is 4-6 hours.

Indications for use

Constipation, cholangitis, cholecystitis, hypotonic type of gallbladder dyskinesia (for tubage), duodenal sounding (to obtain a gallbladder portion of bile), bowel cleansing before diagnostic manipulations. Poisoning with salts of heavy metals (mercury, arsenic, tetraethyl lead, barium).

Magnesium chloride, although it is an inorganic salt, is very strongly absorbed. Raul Verghini says that "this is only true for severe kidney failure" where there may be a clear contraindication, but this also applies to all minerals that cannot be easily eliminated with a serious compromised kidney. The amount of magnesium Alumina contained in a solution of 2.5% solution of 125 cm 3 is about 500 mg. This was introduced very slowly and the results were very good, as well as a Myers cocktail containing 2 to 5 ml of a 20% magnesium chloride solution.

Method of application and dosing regimen

Inside, it is prescribed as a laxative (at night or on an empty stomach - half an hour before meals) for adults, dissolve 10-30 g of powder in 100 ml of warm boiled water. For chronic constipation - enemas (20 - 30 g of powder dissolved in 100 ml of warm boiled water).

As a choleretic agent, 1 tablespoon of the solution is prescribed (20 g of the powder is dissolved in 100 ml of warm boiled water) 3 times a day; duodenal sounding is also performed with the introduction of a warm solution of magnesium sulfate through the probe (50 ml of a 25% solution or 100 ml of a 10% solution).

More detailed information can be found here. Magnesium sulfate, also called magnesium sulfate, is a salt of sulfuric acid, it is a white, odorless and bitter powder. Its crystal structure contains 7 water molecules, so it is defined as a heptahydrate. One gram of the product provides 100mg of magnesium, but there are not many scientific studies regarding the level of minerals in the body after ingestion. Magnesium sulfate is generally considered to be poorly absorbed, and if researchers want to use it as a supplement, some scientists recommend forms that provide greater bioavailability.

Side effect

Nausea, vomiting, diarrhea, exacerbation of inflammatory diseases of the gastrointestinal tract, electrolyte imbalance (fatigue, asthenia, confusion, arrhythmia, convulsions), flatulence, spastic abdominal pain, thirst, signs of hypermagnesemia in the presence of renal failure (dizziness).

Indications for use

These include organic salts or magnesium chloride. Magnesium sulfate is widely used for its laxative function when administered orally and is known as Epsom salts or Epsom salts. Depending on the amount used, typically about 20 g per day, the compound may be a saline laxative or an osmotic purge. Taking such high doses, most of the salt is not absorbed by the intestines and causes water to osmosis. Therefore, the substance increases the water content of the faeces, which reach a softer or even liquid consistency which makes it easier to remove.

Early signs and symptoms of hypermagnesemia: bradycardia, diplopia, sudden "rush" of blood to the skin of the face, headache, lowering blood pressure, nausea, shortness of breath, blurred speech, vomiting, weakness.

Signs of hypermagnesemia (in order of increasing serum Mg2+ concentrations): decreased deep tendon reflexes (2 - 3.5 mmol / l), prolongation of the P-Q interval and expansion of the QRS complex on the ECG (2.5 - 5 mmol / l), loss of deep tendon reflexes (4 - 5 mmol / l), depression of the respiratory center (5 - 6.5 mmol / l), impaired conduction of the heart (7.5 mmol / l), cardiac arrest (12.5 mmol / l). In addition, hyperhidrosis, anxiety, deep sedation, polyuria, uterine atony.

Contraindications

Hypersensitivity, appendicitis, rectal bleeding (including suspected), intestinal obstruction, dehydration, hypermagnesemia.

Precautionary measures

The drug should be taken occasionally. Systematic use is not recommended.

Interaction with other drugs

Reduces the effect of oral anticoagulants (including coumarin derivatives or indandione derivatives), cardiac glycosides, phenothiazines (especially chlorpromazine).

Reduces the absorption of ciprofloxacin, etidronic acid, antibiotics of the tetracycline group (forms unabsorbed complexes with oral tetracyclines), weakens the effect of streptomycin and tobramycin (laxatives Mg2 +-containing drugs should be taken 1-2 hours after the use of the above drugs).

Pharmaceutically incompatible (precipitates) with Ca2+ preparations, ethanol (in high concentrations), alkali metal carbonates, bicarbonates and phosphates, arsenic acid, barium, strontium salts, clindamycin phosphate, sodium hydrocortisone succinate, polymyxin B sulfate, procaine hydrochloride, salicylates and tartrates .

Overdose

Symptoms: severe diarrhea. Treatment is symptomatic.

Release form

Powder for solution for internal use, 10 g or 20 g per sachet.

Information on drug registration

See also